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Moonchild Nigeria
Student @ Gombe State University
Gombe, Nigeria
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In Literature, Writing and Blogging 2 min read
When pharmacology became personal
<h3><em style=""><strong>Hear me out😭</strong></em></h3><p>I'm not about to give you another health lecture.</p><p>If you're a health student reading this,you'll understand me 😹😭. Pharmacology on paper is different from when you're the one experiencing it. The PK and PD sounds great,the side effects look abstract. Until you're the one experiencing it. </p><p>I was recently sick and admitted in the hospital,and hated every bit of it 😭let's not even talk about the smell of the hospital. </p><p>You see those drugs? It's like they made me more sick 😂😭I couldn't take it. I had to settle for injections (which I absolutely prefer). A single pill is enough to make me nauseous and short of breath 😭 I was literally fighting to survive the drug's side effects,instead of feeling better. </p><p>But the one that made me pause is the antimalarials (btw therapy has been extended to five days,and no longer three...thank God I'm done with my course😂😭),I was like "<em>Khairat you cannot study pharmaceutics and medicinal chemistry in vain,how can we make these drugs more palatable and improve patient's compliance,while maintaining maximum efficacy?</em>". </p><p>Because honestly,one of the many reasons for therapeutic failure is lack of compliance by patients. I mean the drug is hard to swallow for crying out loud 😭. </p><p>And because I've been searching for a topic to research on lately,I finally settle on antimalarials and patient compliance. </p><p><strong><em>Hear me out!!</em></strong></p><p>It's not going to be easy, because most of the active ingredients used in formulating the drug itself are extremely bitter. If you're from the early 2000s(I'm not😅but I've learned about it), you'll know chloroquine and how bitter it was. Quinine and quinidine are extremely bitter,so masking the taste and smell is a difficult thing. I know there are drugs that have addressed some of these,but they have some major side effects and formulation problems .</p><p>I'm thinking towards a drug with less side effects  (cuz we can't have a drug with zero side effects),but better efficacy and one that  improves patient compliance. That is the whole essence of therapy.</p><p>There will be issues of excipients, bioavailability, metabolism....name it. But I'm hoping it'll turn out well.</p><p>And I'm taking my health very seriously now 😂 na to dey carry mosquito repellent and food around, because I cannot experience this again 😭 😭 </p><p>I still can't tolerate any strong scent. Just thinking of any drug makes me sick sef 😭 </p>

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